Aerobic fitness exercise induces mitochondrial biogenesis plus an increased capacity regarding oxidative phosphorylation in the mitochondria of skeletal muscle tissue, which is one system by which aerobic physical exercise enhances submaximal endurance performance. These effects occur through an exercise-induced increase within the intracellular AMP: ATP ratio, thereby triggering the activation of AMP-activated proteins kinase (AMPK) which eventually phosphorylates peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α), the particular master regulator of mitochondrial biogenesis.Other peripheral organs Bowflex Treadclimber Workout Plan LIVESTRONG.COM Best 25+ Bowflex workout ideas on Pinterest Cable machine workout, Weight machine workout and Bodybuilding With Bowflex Xtreme How To Use A Bowflex For Bodybuilding BodyBuilding eStore 30 Minute FullBody Interval Workout Circuit Bowflex Summary of long-term adaptations to regular aerobic plus anaerobic exercise. Aero